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News, opinions and meeting coverage in rheumatology.

A bottle and tablet of Rinvoq (upadacitinib) over an x-ray image of a spine with ankylosing spondylitis

Rinvoq Shows Promise in Spine Disease

1-year results in ankylosing spondylitis demonstrate efficacy for JAK inhibitor upadacitinib

EULAR over a computer rendering of human body parts with the major joints glowing red

Oral JAK 1 Inhibitor Eases Spine Inflammation in Ankylosing Spondylitis

Treatment with filgotinib resulted in significant improvements compared with placebo

A Taltz (ixekizumab) auto injector pen over a photo of a mans back, his spine highlighted in red

Stopping IL-17 Drug for Axial Spondyloarthritis? Expect Spinal Flares

But low disease activity regained if treatment restarted

Bags of fentanyl tablets seized by the Drug Enforcement Agency

ED Docs Split Over Fentanyl Analogue Schedule 1 Extension

Will it save lives or prevent drug users from seeking help?

A computer rendering of a human pelvis and spine, the sacroiliac joints and spine are highlighted in red

Delayed Diagnosis Common in Spinal Ailment

Typical 7-year delay after symptom onset leaves patients at risk for irreversible damage

A Cosentyx injection pen over a hand with psoriasis

Spinal Benefits Seen With Cosentyx in PsA

First trial to evaluate response of axial symptoms in psoriatic arthritis to biologic treatment

NSAIDs over a pregnant woman holding a white tablet and glass of water above FDA WARNING

FDA Warns Against NSAIDs in Pregnancy After 20 Weeks

Risk of kidney complications and low amniotic fluids may jeopardize fetus

ASIPP over a close up photo of a senior man's pained face with a tear falling

Pulsed RF Therapy Reduces Pain

Mechanism of action pursued in meta-analysis

ASIPP over a close up photo of a senior man's pained face with a tear falling

Falls Blamed for Pain Relief Device Failure

Damage found while testing after patient complains of pain recurrence

ASIPP over a close up photo of a senior man's pained face with a tear falling

Novel Form of Muscle Relaxant Shows Benefit

Tolperisone may help pain from acute back spasms without causing drowsiness

A doctor fills out a prescription on an RX pad

Muscle Relaxer Rx Doubled Over 12-Year Span

Spike in prescriptions among older adults particularly concerning, researchers note

A photo of Queen guitarist Brian May performing.

Queen Guitarist's Agonizing May

Sciatica + "small heart attack" = trying time for Brian May

An x-ray image of a man鈥檚 spine with ankylosing spondylitis

IL-17A Blockers Succeed in Spine Disease

Secukinumab and ixekizumab best placebo for ankylosing spondylitis

An x-ray image of a spine with ankylosing spondylitis

IL-17A/F Inhibitor a Winner in Spine Disease

Targeting both cytokines had rapid, sustained benefits in ankylosing spondylitis

A mature woman in her kitchen experiencing back pain

Postmenopausal Low Back Pain: Is Lack of Vitamin D the Problem?

Finding "speaks to the importance of avoiding severe vitamin D deficiency states"

A computer rendering of a transparent body with the spine highlighted signifying pain and the persons hand on their back

New Use for Methotrexate in Spondyloarthritis?

In combination with adalimumab, immunogenicity lowered by half in patients with axial SpA

A close up of an elderly woman shaking some aspirin out of a bottle into her hand

More Evidence That Aspirin Can Stave Off Death

PLCO follow-up data support protective effect

American Pain Society Goes Belly Up

Opioid lawsuit costs prompt membership to approve bankruptcy filing

In Spine Disease, One Clear Risk Factor for Relapse

Most occurred after treatment withdrawal among patients on infliximab

Pain: Yes, There's an App for That

But meta-analysis suggests benefit is just a few tenths of a point on standard 0-10 scale

Gabapentin Plus Opioids for Chronic Pain?

Small study shows no superiority over opioids alone

Whole-Body Cyrotherapy Caused Cold Burn Injury

Trendy treatment never FDA-approved for health benefits

Radiofrequency Pulses End Back Pain

Probes guided to herniated disk appears to enhance pain relief and healing

NSAIDs OK for Certain High-Risk Groups?

No obvious harm seen in HTN, HF, or chronic kidney disease

Repeat CRP Tests If Spine Disease Uncertain

Post-hoc analysis of patients with axial spondyloarthritis

Mumps and Boosters; Ecigs and Quitting: It's PodMed Double T!

This week's topics include sinusitis treatment, low back pain management, waning mumps immunity, and e-cigarettes and quitting attempts

Sensitivity Heightened with Chronic Low Back Pain

Catastrophizing is also a common feature

Injecting Arthritic Knees Carries Sepsis Risk

Study identified four risk factors for sepsis after injections for knee pain.

Remission Common in Early SpA With Golimumab

Drug-free remission maintained for more than half after at least 12 months

Are Statins Behind Some Back Problems?

Claims data suggest association, but cardiologists urge caution

Pre-TKA Opioid Script Predicts Post-Op Prescription

Especially prevalent after 6 months post-op

Pearls From: Rheumatologist Philip Mease

An expert discusses new treatments for PsA and SpA

Denervation Tx Helps Patients With Discogenic Back Pain

Biacuplasty plus conventional treatment provided relief in trial

Medical Schools Boost Pain Management Education

In light of opioid epidemic, more schools focus on thoughtful prescribing

Prednisone Offers Modest Relief in Sciatica

Oral steroids are commonly used but without much supporting evidence.

Separating Spondyloarthritis From Back Pain Still Problematic

Spinal MRI criteria don't help differentiate SpA from nonspecific pain.

FDA Panel Wants Safer Epidural Steroid Shots

Majority votes to end epidural injections with "particulate" steroids.

FDA Advisers Tackle Epidural Steroid Shots

Focus on adverse neurologic effects.

Humira Benefits Persist in Spine Disease

Anti-TNF treatment efficacy maintained at 3 years in axial spondyloarthritis.

Now What? DEA Tosses Tramadol in Schedule IV

The Drug Enforcement Administration (DEA) scheduled tramadol as a Schedule IV substance -- whats the big fuss about tramadol that led to this decision by the DEA?

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