Low-Dose 'Quadpill' Reduces High Blood Pressure Significantly lower diastolic blood pressure at 12 weeks, U.S.-based study showed Nov 09, 2022
Strong Showing for Novel BP-Lowering Drugs in Resistant Hypertension Aprocitentan targets the endothelin pathway, whereas baxdrostat blocks aldosterone production Nov 09, 2022
Can Botox for the Heart Ward Off Afib After Cardiac Surgery? Epicardial botulinum toxin generally not better than placebo in the NOVA study Nov 09, 2022
Precision Medicine Strategy Reduced Testing in Patients With Chest Pain Also reduced risk of composite endpoint of death, MI, and catheterization compared with usual care Nov 08, 2022
Anticoagulation Again Flops for Outpatient COVID-19 Largest-yet RCT shows no benefit for non-hospitalized symptomatic patients despite elevated risk Nov 08, 2022
Upfront ECMO Disappoints for Cardiogenic Shock High-cost procedure not yet justified as an early strategy Nov 07, 2022
Moving Fast on HF Drugs After Acute Hospitalization Holds Big Outcome Benefit Randomized trial shows advantages across heart failure spectrum Nov 07, 2022
Bivalirudin Crowned as Better Anticoagulant for Primary PCI in STEMI BRIGHT-4 trial hands the drug a "clear, unambiguous win" against heparin Nov 07, 2022
Early Invasive Strategy for Stable CAD Holds No Long-Term Survival Advantage Extended follow-up of ISCHEMIA trial weighs in on mortality Nov 07, 2022
Experts Agree Intravenous Iron Shows Promise for Heart Failure Patients While findings were not significant, the study was impacted by COVID lockdowns, researcher says Nov 07, 2022
Study Refutes Heart Health Claims of Dietary Supplements LDL cholesterol reductions with cinnamon, garlic, and others not on par with statin Nov 06, 2022
Decision-Support Tool Enhances Outcomes for Heart Failure Patients in the ED Pathways for HF patients picked for early discharge versus admission Nov 06, 2022
Definitive Answer on Steroids for Infant Heart Surgery Falls Short STRESS trial misses primary endpoint but secondary benefits are suggestive Nov 06, 2022
Diuretics on Par in Head-to-Head Comparison for Hypertension But a surprise signal emerges for one group in pragmatic trial Nov 06, 2022
Mixed Results With Pemafibrate in Patients With Type 2 Diabetes No impact on CV events in PROMINENT; developer brings trial to an end Nov 06, 2022
Furosemide Holds Up to Newer, Stronger Loop Diuretic During HF Hospitalization Preference for mainstay decongestant versus torsemide likely unchanged after TRANSFORM-HF study Nov 05, 2022
Bentracimab on Point as Fast-Acting Ticagrelor Reversal Agent "Immediate and sustained" benefit, interim REVERSE-IT analysis found Nov 17, 2021
Oral Factor XIa Inhibitor Sets the Stage for a Safer Anticoagulant Milvexian shows promise in preventing vein clots after total knee replacement surgery Nov 16, 2021
Potent Antiplatelet Not a Good Idea for Moderate COVID-19 ACTIV-4a trial suggests harm for hospitalized patients outside the ICU Nov 16, 2021
Hospitalized Acute HF Patients See Clinical Benefits With Empagliflozin EMPULSE results support early start for the SGLT2 inhibitor, but more data needed, expert says Nov 16, 2021
Vascepa Succumbs as COVID Treatment in 'Underpowered' Trial Purified fish oil didn't help SARS-CoV-2-positive outpatients Nov 15, 2021
Aspirin Flops Again for Dementia Prevention ASCEND trial sides with ASPREE, but can't rule out some potential benefit Nov 15, 2021
Stem Cells Don't Prevent Acute Heart Failure Events DREAM-HF trial does hold some positive signals, though Nov 15, 2021
Some Good News for Curious Afib Patients Looking to Find Their Own Triggers Presumed Afib triggers put to the test in n-of-1 studies Nov 14, 2021
PALACS: A Win for Posterior Left Pericardiotomy for Post-Op Afib Trial offers good news for patients getting coronary, aortic valve, and aortic surgeries Nov 14, 2021
Two Anticoagulants -- When Used Correctly -- Similarly Protective Against Dementia GIRAF trial tested warfarin versus dabigatran in older Afib patients Nov 14, 2021
Coffee Causes This One Arrhythmia, Trial Shows Overall mixed results in the CRAVE randomized trial Nov 14, 2021
Tricuspid Repair Boosts Mitral Valve Surgery Outcomes Randomized trial supports combined surgery for moderate regurgitation Nov 13, 2021
Delaying Surgery Hurts Patients With Silent Aortic Stenosis Early aortic valve replacement wins in AVATAR trial Nov 13, 2021
Early CABG After Stopping Ticagrelor is Possible -- But is It Ready for Prime-Time? RAPID CABG shows non-inferority of shorter wait; expert advises caution for real-world practice Nov 13, 2021
Antibiotics Slow Down Latent Rheumatic Heart Disease in Kids GOAL trial supports screening Nov 13, 2021
COVID's Heart Complications Modest in Large Registry Obese and minority groups at higher risk, though, analyses affirm Nov 18, 2020
AHA: Highlighting Effective 'Real-World' Heart Tx Strategies Studies on overcoming GDMT underuse, improving self-care education, creating new settings for care delivery Nov 17, 2020
Post-Surgery Monitoring Finds Afib in Discharged Patients About 20% of patients had episodes recorded on devices, study showed Nov 17, 2020
Sotagliflozin Prevents Heart Events in Acute HF, Chronic Kidney Disease Two trials show some tantalizing signals for HFpEF and stroke Nov 17, 2020
Novel Screening Approach Promising for Silent CAD More than 40% of healthy Swedish participants still had subclinical coronary artery disease Nov 16, 2020
VITAL-AF, mSToPS: Mixed Results in Afib Screening A signal that screening by continuous ECG monitoring leads to better outcomes Nov 16, 2020
Skip Rhythm Drugs, Go Straight to Cryoablation for Afib Two trials support shift into first-line strategy Nov 16, 2020
ANGPTL3 Blocker Halves LDL in High-Risk Group Evinacumab worked in patients refractory to statins, PCSK9 inhibitors Nov 16, 2020
